Background: With the improved lifestyle of people, the incidence of coronary\nartery disease is gradually increasing. Approximately 15% - 20% of patients\nundergoing diagnostic catheterization had one or more chronically occluded\ncoronary arteries. Method: The patients who were diagnosed with chronic\ntotal occlusion (CTO) in our hospital within one year period have been included.\nThey were initially divided into two groups based on angiographic\nreports: single vessel disease (SVD) and non-single vessel disease (non-SVD)\ngroup, then into optimal medical therapy (OMT) group, percutaneous coronary\nintervention (PCI) group and coronary artery bypass graft (CABG) group.\nFinally, PCI group is further divided into PCI of CTO lesion (CTO PCI group)\nand PCI of non-CTO lesion (non-CTO PCI group). Results: A total of 261 patients\nwere enrolled as CTO patients, mean age was 62.83 years, 70.1% were\nmale patients. The incidence rate of common risk factors was hypertension\n(64.4%), followed by smoking (48.3%), diabetes (34.5%) and hyperlipidaemia\n(27.2%). SVD, DVD and TVD were present in 39 patients (14.94%), 81 patients\n(31.03%) and 141 patients (54.02%) respectively. Comparing the long term efficacy,\nthe rates of MACE and non-target vessel revascularization were higher\nin CTO PCI than non-CTO PCI group, and were statistically significant (p <\n0.05). The rates of target vessel revascularization, CABG and all cause death\nwere also lower in CTO PCI group, but were not statistically significant (p >\n0.05). Conclusion: The rates of MACE, non-target vessel revascularization,\nCABG and all cause death are lower if PCI is successfully performed in CTO\npatients. CTO PCI success also improves quality of life, decreases myocardial\nischemia induced angina, and overall improves long term efficacy.
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